Aromatic nucleophilic substitution reactions of activated N-arylpyrazoles with formamides

被引：0
|
作者：
Chiriac, CI
Lupu, V
Chiriac, F
Ropot, R
Tibirna, M
Truscan, I
机构：
来源：
REVUE ROUMAINE DE CHIMIE | 1995年 / 40卷 / 06期
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中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Different activated N-arylpyrazoles, as N-(2',4'-dinitrophenyl)-3,5-dimethylpyrazole, N-picryl-3-5-dimethylpyrazole etc., can react with excess formamides, as formamide N-methylformamide and N,N-dimetylformamide, at 165-175 degrees C, for 5-6 hours, resulting amines in high yields. This reaction is influenced by steric hindrance.
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页码：549 / 553
页数：5
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