Bradykinin-mediated angioedema

被引：1

作者：

Javaud, N. ^{[1
,2
]}

Fain, O. ^{[1
,3
]}

Martin, L. ^{[1
,4
]}

机构：

[1] Ctr Reference Angioedemes Kinines, CREAK, St Denis, Reunion, France

[2] Univ Paris 13, Hopitaux Univ, Serv Urgences, SAMU SMUR 93, St Denis, Reunion, France

[3] Univ Paris 13, Hopitaux Univ, Serv Med Interne, SAMU SMUR 93, St Denis, Reunion, France

[4] Univ UNAM, CHU Angers, Serv Dermatol, St Denis, Reunion, France

来源：

REANIMATION | 2013年 / 22卷 / 05期

关键词：

Bradykinin; Drug-induced angioedema; Emergency; Hereditary angioedema;

D O I：

10.1007/s13546-013-0696-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Bradykinin-mediated angioedema (AE) is characterized by periodic subcutaneous or submucosal swelling, with the absence of urticaria and itching. AE involves the face and extremities. Attacks of abdominal pain and obstruction of the upper airways are the hallmarks of disease severity. There are hereditary and acquired forms, including cases secondary to the administration of converting enzyme-inhibitors. Acute attacks are treated by early administration of specific treatments, including icatibant, an inhibitor of bradykinin B2 receptor and C1-inhibitor concentrate.

引用

页码：449 / 454

页数：6

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