Prophylactic Efficacy of Adsorbents in Case of Combined Impact of T-2 and Aflatoxin B1 on the Organism of the Mink

The aim of the research was to study the preventive treatment in case of combined impact of T-2 and aflatoxin B1 mycotoxinson the organism of the mink. The experiment was conducted in Pastel minks. Minks were divided into four groups of 10 animals each. Group 1 served as biological control. Group 2 received T-2 toxin at a dose of 200 mu g/kg and aflatoxin B1 at a dose of 50 mu g/kg of feed in addition to the basic ration. Group 3 received T-2 toxin at a dose of 200 mu g/kg, aflatoxin B1 at a dose of 50 mu g/kg of feed and sodium bentonite at a dose of 2% of the weight of the ration. Group 4 received T-2 toxin at a dose of 200 mu g/kg, aflatoxin B1 at a dose of 50 mu g/kg of feed and phytosorb at a dose of 0.5% of the weight of the ration. The experiment lasted 30 days, hematological and biochemical blood tests were performed every 10 days. Doses of toxins were taken according to the currently existing maximum permissible levels in Russia. The data obtained were compared with those of the biological control group. The results of the experiment indicate that the intake of mink feed containing simultaneously two mycotoxins - T-2 toxin and aflatoxin B1causes pronounced and statistically significant changes in hematological and biochemical parameters towards their deterioration. The addition of bentonite from Tarn-Varskoe deposit at a dose of 2% and enterosorbent Phytosorbat a dose of 0.5% of the weight of the feed to the ration of animals has a preventive effect in case of T-2 and aflatoxicosis in minks with the normalization of hematological, biochemical and biological parameters.