INTRATHECAL SYNTHESIS OF VIRUS-ANTIBODIES - A DIAGNOSTIC-TEST FOR MULTIPLE-SCLEROSIS

被引：2
|
作者：
SCHADLICH, HJ [1 ]
MOHRMANN, G [1 ]
NEKIC, M [1 ]
FELGENHAUER, K [1 ]
机构：
[1] UNIV GOTTINGEN,W-3400 GOTTINGEN,GERMANY
来源：
EUROPEAN NEUROLOGY | 1990年 / 30卷 / 05期
关键词：
Intrathecal synthesis; Multiple sclerosis; Virus antibodies;
D O I：
10.1159/000117385
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Intrathecally synthesized antibodies against measles and rubella were determined in 221 patients with multiple sclerosis (MS) and in 476 control cases. A local production was detectable in more than 80% of the MS cases but in none of the control group. These results show that the demonstration of intrathecally synthesized antibodies against neurotropic viruses not related with respective infections may serve as helpful test in the diagnosis of MS.
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页码：302 / 304
页数：3
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