SERUM LEVELS OF FLURITHROMYCIN ETHYLSUCCINATE IN HEALTHY-VOLUNTEERS

被引：2
|
作者：
COCUZZA, CE
MATTINA, R
LANZAFAME, A
ROMOLI, L
LEPORE, AM
机构：
[1] UNIV MILAN,SCH MED,INST MED MICROBIOL,I-20133 MILAN,ITALY
[2] PIERREL SPA,CLIN RES & DEV,MILAN,ITALY
来源：
CHEMOTHERAPY | 1994年 / 40卷 / 03期
关键词：
FLURITHROMYCIN ETHYLSUCCINATE; PHARMACOKINETICS; SERUM LEVELS;
D O I：
10.1159/000239187
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The serum levels of flurithromycin ethylsuccinate achieved 30 min after a single oral dose of 375 mg were found to be equal or above the minimal inhibitory concentrations for sensitive strains, when administered to 12 healthy volunteers. The serum half-life was found to be approximately 4 h.
引用
收藏
页码：157 / 160
页数：4
相关论文
共 50 条
  • [41] HIV SCREENING IN HEALTHY-VOLUNTEERS
    HARRY, JD
    BABER, N
    POSNER, J
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1995, 39 (02) : 213 - 214
  • [42] BIOAVAILABILITY OF NAFARELIN IN HEALTHY-VOLUNTEERS
    CHAPLIN, MD
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1992, 166 (02) : 762 - 765
  • [43] THE PHARMACOKINETICS OF CHLOROQUINE IN HEALTHY-VOLUNTEERS
    WALKER, O
    ALVAN, G
    BEERMANN, B
    GUSTAFSSON, LL
    LINDSTROM, BL
    SJOQVIST, F
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1982, 14 (04) : P624 - P624
  • [44] RESEARCH ON HEALTHY-VOLUNTEERS - A REPORT
    不详
    JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF LONDON, 1986, 20 (04): : 243 - 257
  • [45] PHARMACOKINETICS OF DEFIBROTIDE IN HEALTHY-VOLUNTEERS
    NOSEDA, G
    FRAGIACOMO, C
    FERRARI, D
    HAEMOSTASIS, 1986, 16 : 26 - 30
  • [46] PHENYTOIN BINDING IN HEALTHY-VOLUNTEERS
    BERG, MJ
    EBERT, BE
    FINCHAM, RW
    SCHOTTELIUS, DD
    THERAPEUTIC DRUG MONITORING, 1987, 9 (04) : 384 - 388
  • [47] HALOPERIDOL PHARMACOKINETICS IN HEALTHY-VOLUNTEERS
    KUNKA, RL
    PEREL, JM
    CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 1989, 45 (06): : 1088 - 1096
  • [48] PHARMACOKINETICS OF ROXATIDINE IN HEALTHY-VOLUNTEERS
    COLLINS, JD
    PIDGEN, AW
    DRUGS, 1988, 35 : 41 - 47
  • [49] PHARMACOKINETICS OF LISINOPRIL IN HEALTHY-VOLUNTEERS
    BEERMANN, B
    GOMEZ, H
    TILL, A
    JUNGGREN, IL
    ACTA PHARMACOLOGICA ET TOXICOLOGICA, 1986, 59 : 66 - 66
  • [50] PHARMACOKINETICS OF CLOPREDNOL IN HEALTHY-VOLUNTEERS
    LEGLER, UF
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 1988, 26 (04) : 173 - 175
12345