SINONASAL HEMANGIOPERICYTOMAS - A CLINICOPATHOLOGICAL AND DNA CONTENT STUDY

被引:0
|
作者
ELNAGGAR, AK [1 ]
BATSAKIS, JG [1 ]
GARCIA, GM [1 ]
LUNA, ML [1 ]
GOEPFERT, H [1 ]
机构
[1] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT HEAD & NECK SURG,HOUSTON,TX 77030
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中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
The clinicopathologic and the flow cytometric DNA characteristics of 14 patients with sinonasal hemangiopericytomas are presented. Patient and tumor characteristics were similar to previously published series. Flow cytometric analysis revealed a diploid DNA pattern and low S-phase in 13 neoplasms and an aneuploid DNA pattern with relatively high S-phase in one. Histopathologically, all diploid and low S-phase neoplasms displayed relatively uniform cellular features and low mitotic counts. All patients are alive and free of disease; one is still alive after a single recurrence. Our data suggest that sinonasal hemangiopericytomas are low-grade neoplasms as evidenced by their histomorphology and their DNA content. Recurrences are delayed and can be controlled.
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页码:134 / 137
页数:4
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