INHIBITION OF LYMPHOCYTE-PROLIFERATION IN-VITRO BY 2 LIPID EMULSIONS WITH DIFFERENT FATTY-ACID COMPOSITIONS

被引：24
|
作者：
CALDER, PC
SHERRINGTON, EJ
ASKANAZI, J
NEWSHOLME, EA
机构：
[1] Department of Biochemistry, University of Oxford, Oxford, OX1 3QU, South Parks Road
[2] Department of Anesthesiology, Mount Sinai School of Medicine, New York, NY 10029, Gustave Levy Place
来源：
CLINICAL NUTRITION | 1994年 / 13卷 / 02期
关键词：
D O I：
10.1016/0261-5614(94)90062-0
中图分类号：
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号：
100403 ;
摘要：
The effects of two lipid emulsions upon the proliferation of rat and human lymphocytes in vitro were investigated. The emulsions used were Intralipid, a soya bean oil-based emulsion in widespread clinical use, and Omegavenous, a newly-developed emulsion in which n-3 polyunsaturated fatty acids comprise approximately 40% of the total fatty acids. Both emulsions inhibited lymphocyte proliferation in a concentration- and time-dependent manner. Omegavenous was a much more potent inhibitor than Intralipid.
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页码：69 / 74
页数：6
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