SIMULTANEOUS DETERMINATION OF CARBAMAZEPINE AND ITS MAJOR METABOLITES IN HUMAN PLASMA AND URINE BY HPLC

被引：6
|
作者：
TSAPROUNIS, CK
KAJBAF, M
GORROD, JW
机构：
[1] UNIV LONDON KINGS COLL,CHELSEA DEPT PHARM,LONDON WC2R 2LS,ENGLAND
[2] UNIV LONDON,LONDON,ENGLAND
来源：
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS | 1991年 / 16卷 / 04期
关键词：
D O I：
10.1111/j.1365-2710.1991.tb00312.x
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A method is described for the analysis of carbamazepine and its major metabolites in biological fluids. The method uses a HPLC system based on a C-18 Partisil column. The metabolites were extracted from chloroform in the presence of an internal standard. The method was specific, precise and reproducible.
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页码：257 / 262
页数：6
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