Pulmonary arterial hypertension associated with hereditary spherocytosis and splenectomy in a patient with a mutation in the BMPR2 gene

被引：4

作者：

Baloira, Adolfo ^{[1
]}

Bastos, Maria ^{[2
]}

Pousada, Guillermo ^{[3
]}

Valverde, Diana ^{[3
]}

机构：

[1] Complejo Hosp Univ Pontevedra, Div Resp, Pontevedra, Spain

[2] Complejo Hosp Univ Pontevedra, Dept Cardiol, Pontevedra, Spain

[3] Univ Vigo, Dept Genet, Fac Biol, Vigo, Spain

来源：

CLINICAL CASE REPORTS | 2016年 / 4卷 / 08期

关键词：

ACVRL1; ambrisentan; BMPR2; hereditary spherocytosis; pulmonary arterial hypertension;

D O I：

10.1002/ccr3.610

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is some question about the relationship between hereditary spherocytosis (HS) and pulmonary arterial hypertension, even associated with splenectomy. The finding of BMPR2 mutations in our patient suggests that other factors are necessary for the development of the disease, and perhaps, the incidence of pulmonary hypertension is not increased in patients with HS.

引用

页码：752 / 755

页数：4

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