EFFECT OF PARTIAL-PRESSURE ON SOLUBILITY OF ISOFLURANE IN BLOOD

被引：0
|
作者：
XIE, GM [1 ]
LAUBER, R [1 ]
ZBINDEN, AM [1 ]
机构：
[1] UNIV HOSP BERN,INST ANAESTHESIOL & INTENS CARE,CH-3010 BERN,SWITZERLAND
来源：
CHINESE MEDICAL JOURNAL | 1995年 / 108卷 / 09期
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中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The effect of partial pressure of isoflurane on its solubility in blood of different haematocrit was determined at different isoflurane partial pressures, using a syringe-flask method and gas chromatography with blood from one donor. The solubility of isoflurane decreased with increasing blood haematocrit (39.5%, 51.9% and 61.9%) and isoflurane partial pressure from 1 MAC to 4 MAC. The solubility in 50% and 60% haematocrit blood at 2, 3 and 4 MAC was significantly different from the solubility in normal blood at 1 MAC (P<0.05). We conclude that the solution of isoflurane in blood (especially in high haematocrit blood) does not obey Henry's law.
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页码：665 / 668
页数：4
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