4-(2-AMINO-1-METHYLIMIDAZO[4,5-B]PYRID-6-YL)PHENYL SULFATE - A MAJOR METABOLITE OF THE FOOD MUTAGEN 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (PHIP) IN THE RAT

被引：54
|
作者：
ALEXANDER, J
WALLIN, H
HOLME, JA
BECHER, G
机构：
来源：
CARCINOGENESIS | 1989年 / 10卷 / 08期
关键词：
D O I：
10.1093/carcin/10.8.1543
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1543 / 1547
页数：5
相关论文
共 50 条
  • [31] METABOLISM OF THE FOOD-DERIVED MUTAGEN CARCINOGEN 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE (PHIP) IN NONHUMAN-PRIMATES
    SNYDERWINE, EG
    BUONARATI, MH
    FELTON, JS
    TURTELTAUB, KW
    CARCINOGENESIS, 1993, 14 (12) : 2517 - 2522
  • [32] 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE IS A POTENT MUTAGEN IN THE MOUSE SMALL-INTESTINE
    BROOKS, RA
    GOODERHAM, NJ
    ZHAO, KC
    EDWARDS, RJ
    HOWARD, LA
    BOOBIS, AR
    WINTON, DJ
    CANCER RESEARCH, 1994, 54 (07) : 1665 - 1671
  • [33] Incorporation of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) into fur and correlation with intestinal tumourigenesis in Min/+ mice
    Steffensen, IL
    Janak, K
    Hegstad, S
    Andreassen, Å
    Paulsen, JE
    Reistad, R
    Alexander, J
    PHARMACOLOGY & TOXICOLOGY, 2003, 92 (03): : 131 - 136
  • [34] ABCG2 decreases the placental transfer of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
    Myllynen, Paivi
    Kummu, Maria
    Pirila, Rauna
    Lastumaki, Anni
    Vahakangas, Kirsi
    TOXICOLOGY LETTERS, 2007, 172 : S187 - S187
  • [35] N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine:: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
    Frandsen, H
    Alexander, J
    CARCINOGENESIS, 2000, 21 (06) : 1197 - 1203
  • [36] Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes
    Langouët, S
    Paehler, A
    Welti, DH
    Kerriguy, N
    Guillouzo, A
    Turesky, RJ
    CARCINOGENESIS, 2002, 23 (01) : 115 - 122
  • [37] THE METABOLIC DISPOSITION OF 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE IN THE INDUCED MOUSE
    TURTELTAUB, KW
    KNIZE, MG
    HEALY, SK
    TUCKER, JD
    FELTON, JS
    FOOD AND CHEMICAL TOXICOLOGY, 1989, 27 (10) : 667 - 673
  • [38] Comparison of crystal structure and theory for 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
    Parkin, S
    Marsch, GA
    Hope, H
    Whitney, E
    Winter, NW
    Colvin, ME
    Felton, JS
    Turteltaub, KW
    CHEMICAL RESEARCH IN TOXICOLOGY, 1996, 9 (03) : 574 - 579
  • [39] FATE AND DISTRIBUTION OF 2-AMINO-1-METHYL-6-PHENYLIMIDAZO-[4,5-B]PYRIDINE (PHIP) IN RATS
    WATKINS, BE
    ESUMI, H
    WAKABAYASHI, K
    NAGAO, M
    SUGIMURA, T
    CARCINOGENESIS, 1991, 12 (06) : 1073 - 1078
  • [40] Detection of 2-amino-1-methyl-6-phenylimidazo [4,5-b]-pyridine (PhIP)-DNA adducts in human pancreatic tissues
    Zhu, J.
    Rashid, A.
    Cleary, K.
    Abbruzzese, J. L.
    Friess, H.
    Takahashi, S.
    Shirai, T.
    Li, D.
    BIOMARKERS, 2006, 11 (04) : 319 - 328
12345