HPR POLYMORPHISM IN ORAL STREPTOCOCCI IS CAUSED BY THE PARTIAL REMOVAL OF THE N-TERMINAL METHIONINE

被引:11
|
作者
VADEBONCOEUR, C
KONISHI, Y
DUMAS, F
GAUTHIER, L
FRENETTE, M
机构
[1] NATL RES COUNCIL CANADA,BIOTECHNOL RES INST,MONTREAL H4P 2R2,QUEBEC,CANADA
[2] UNIV LAVAL,SCH DENT,QUEBEC CITY G1K 7P4,QUEBEC,CANADA
基金
英国医学研究理事会;
关键词
HPR; N-TERMINAL METHIONINE; STREPTOCOCCI; PROTEIN MODIFICATION;
D O I
10.1016/0300-9084(91)90174-Y
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
HPr is a small phosphocarrier protein of the bacterial phosphoenolpyruvate:sugar phosphotransferase system involved in the transport and phosphorylation of sugars. It has recently been reported that streptococci possess two forms of HPr having identical biochemical properties. In this communication, we show by N-terminal amino-acid sequencing and by ion-spray mass spectroscopy that these two forms differ by the presence or the absence of the N-terminal methionine.
引用
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页码:1427 / 1430
页数:4
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