DEPHOSPHORYLATION OF MICROTUBULE ASSOCIATED PROTEIN TAU FROM ALZHEIMER-DISEASE BRAIN INCREASES ITS ABILITY TO PROMOTE INVITRO ASSEMBLY OF MICROTUBULES

被引：0
|
作者：
IQBAL, K [1 ]
KOEPKESECUNDO, E [1 ]
GRUNDKEIQBAL, I [1 ]
机构：
[1] NEW YORK STATE INST BASIC RES DEV DISABILITIES,STATEN ISL,NY 10314
来源：
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY | 1991年 / 50卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：316 / 316
页数：1
相关论文
共 50 条
  • [31] Tau phosphorylation at serine 396 and serine 404 by human recombinant tau protein kinase II inhibits tau's ability to promote microtubule assembly
    Evans, DB
    Rank, KB
    Bhattacharya, K
    Thomsen, DR
    Gurney, ME
    Sharma, SK
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (32) : 24977 - 24983
  • [32] Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans
    Goedert, M
    Jakes, R
    Spillantini, MG
    Hasegawa, M
    Smith, MJ
    Crowther, RA
    NATURE, 1996, 383 (6600) : 550 - 553
  • [33] ALZHEIMER CYTOSKELETAL PATHOLOGY - FROM MICROTUBULE ASSOCIATED PROTEIN TAU TO PAIRED HELICAL FILAMENTS
    GRUNDKEIQBAL, I
    IQBAL, K
    NEUROBIOLOGY OF AGING, 1990, 11 (03) : 331 - 331
  • [34] Glycosylation of microtubule-associated protein tau: An abnormal posttranslational modification in Alzheimer's disease
    Wang, JZ
    GrundkeIqbal, I
    Iqbal, K
    NATURE MEDICINE, 1996, 2 (08) : 871 - 875
  • [35] Intracellular and extracellular microtubule associated protein tau as a therapeutic target in Alzheimer disease and other tauopathies
    Avila, Jesus
    Pallas, Noemi
    Bolos, Marta
    Laura Sayas, C.
    Hernandez, Felix
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2016, 20 (06) : 653 - 661
  • [36] Intracellular Clusterin Interacts with Brain Isoforms of the Bridging Integrator 1 and with the Microtubule-Associated Protein Tau in Alzheimer's Disease
    Zhou, Yuan
    Hayashi, Ikuo
    Wong, Jacky
    Tugusheva, Katherine
    Renger, John J.
    Zerbinatti, Celina
    PLOS ONE, 2014, 9 (07):
  • [37] Natural osmolyte trimethylamine N-oxide can promote phosphorylated microtubule-associated protein tau to stimulate microtubule assembly
    Tseng, HC
    Lu, Q
    Henderson, E
    Graves, DJ
    FASEB JOURNAL, 1999, 13 (07): : A1489 - A1489
  • [38] Microtubule-associated protein tau is a substrate of ubiquitin-proteosomal system - Implication of tau accumulation in Alzheimer disease
    Yu, ZJ
    Jian-Zhi, W
    NEUROBIOLOGY OF AGING, 2004, 25 : S418 - S418
  • [39] A NEW PROTEIN FACTOR THAT MODULATES MICROTUBULE ASSEMBLY INVITRO - EVIDENCE FOR ITS BINDING TO MICROTUBULE-ASSOCIATED PROTEINS
    NISHIDA, E
    SAKAI, H
    BIOMEDICAL RESEARCH-TOKYO, 1981, 2 (01): : 45 - 51
  • [40] HIGH MOLECULAR-WEIGHT PROTEIN MAP-2 PROMOTING MICROTUBULE ASSEMBLY INVITRO IS ASSOCIATED WITH MICROTUBULES IN CELLS
    KUZNETSOV, SA
    RODIONOV, VI
    BERSHADSKY, AD
    GELFAND, VI
    ROSENBLAT, VA
    CELL BIOLOGY INTERNATIONAL REPORTS, 1980, 4 (11) : 1017 - 1024
12345