Comparison of binary data imputation methods in clinical trials

被引:0
|
作者
An, Koosung [1 ]
Kim, Dongjae [1 ]
机构
[1] Catholic Univ Korea, Dept Biomed, Hlth Sci, 222 Banpo Daero Seocho Gu, Seoul 06591, South Korea
关键词
binary missing data; clinical trial; missing pattern; missing data imputation;
D O I
10.5351/KJAS.2016.29.3.539
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
We discussed how to handle missing binary data clinical trials. Patterns of occurring missing data are discussed and introduce missing binary data imputation methods that include the modified method. A simulation is performed by modifying actual data for each method. The condition of this simulation is controlled by a response rate and a missing value rate. We list the simulation results for each method and discussed them at the end of this paper.
引用
收藏
页码:539 / 547
页数:9
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