STEREOSELECTIVE SYNTHESIS OF INOSITOL PHOSPHATES

被引：38
|
作者：
LEY, SV
机构：
[1] Department of Chemistry, Imperial College of Science, Technology and Medicine, London
来源：
PURE AND APPLIED CHEMISTRY | 1990年 / 62卷 / 10期
关键词：
D O I：
10.1351/pac199062102031
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Pseudomonas putida oxidation of benzene affords cis-3,5-cyclohexadiene-l,2-diol (1) which serves as a novel precursor for the syntheses of several natural products including (+)-pinitol, (+)-conduritol F, D-(-)-myo-inositol 1,4,5-trisphosphate and D-mya-inositol 1-phosphate. The versatility of this approach is further demonstrated by the preparation of other functionalised cyclitol derivatives, in particular 6-deoxy, 6-deoxy-6-fluoro, 6-deoxy-6-methyl and 6-methyl inositol 1,4,5-trisphosphates. © 1990, IUPAC.
引用
收藏
页码：2031 / 2034
页数：4
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