METABOLIC CHANGES FOLLOWING CORTICAL CONTUSION - RELATIONSHIPS TO EDEMA AND MORPHOLOGICAL-CHANGES

被引:0
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作者
SUTTON, RL
HOVDA, DA
ADELSON, PD
BENZEL, EC
BECKER, DP
机构
[1] UNIV NEW MEXICO, DIV NEUROSURG, ALBUQUERQUE, NM 87131 USA
[2] UNIV NEW MEXICO, DIV NEUROSURG, ALBUQUERQUE, NM 87131 USA
关键词
CEREBRAL EDEMA; CORTICAL CONTUSION; GLYCOLYSIS; ISCHEMIA; NECROSIS;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Rats with contusion injury to the right cortex exhibited significant formation of edema 6 and 24 hours after injury which resolved by 8 days and was replaced by cavitation necrosis. The contusions produced hyperglycolysis and ischemia in the impacted cortical tissue and underlying hippocampus immediately through 30 minutes post-injury. Glucose utilization was depressed throughout the contused cortex and in ipsilateral subcortical regions, as was blood flow, at chronic (1 and 10 days) periods after injury.
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页码:446 / 448
页数:3
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