The authors analyse the causes of 170 (38.3 %) complications which occurred after 435 interventions for selective proximal vagotomy (SPV) with or without a stomach-draining operation. Specific complications were encountered in 31.9 % and unspecific complications in 7.0 % of cases. Intraoperative complications happen, in 6 (3.6 %) patients who had complications after vagotomy, early complications - in 54 (31.5 %), and late complications - in 79 (46-8 %) patients. The main causes of the specific complications were technical faults in performing SPV, disorder of gastric secretory, motor-evacuation, and barrier activity due to incomplete, inadequte vagotomy. inadequate drainage and disorders of the immune system and dietary regimen, gastroduodenal reflux are conducive to the development of complications after SPV. Reconstructive-restorative operations and resection of the stomach are the operations of choice in organic complications after SPV and produce good late-term results.