5-FLUOROURACIL-METHOTREXATE SYNERGY - ENHANCEMENT OF 5-FLUORODEOXYURIDYLATE BINDING TO THYMIDYLATE SYNTHASE BY DIHYDROPTEROYLPOLYGLUTAMATES

被引：74
|
作者：
FERNANDES, DJ [1 ]
BERTINO, JR [1 ]
机构：
[1] YALE UNIV,SCH MED,DEPT MED,NEW HAVEN,CT 06510
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1980年 / 77卷 / 10期
关键词：
D O I：
10.1073/pnas.77.10.5663
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：5663 / 5667
页数：5
相关论文
共 50 条
  • [41] Role of genomic factors beyond thymidylate synthase in the prediction of response to 5-fluorouracil
    Peters, Godefridus J.
    Smid, K.
    Meijer, E.
    Van Groeningen, C. J.
    Leon, L. G.
    NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS, 2016, 35 (10-12): : 595 - 603
  • [42] Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity
    Etienne, MC
    Ilc, K
    Formento, JL
    Laurent-Puig, P
    Formento, P
    Cheradame, S
    Fischel, JL
    Milano, G
    BRITISH JOURNAL OF CANCER, 2004, 90 (02) : 526 - 534
  • [43] Thymidylate synthase polymorphism in Mexican patients with colon cancer treated with 5-fluorouracil
    Patricia Rios-Ibarra, Clara
    Janeth Rodriguez-Silva, Claudia
    Alonso Lopez-Chuken, Yamil
    Ortiz-Lopez, Rocio
    Fernandez-Castillo, Elisa
    Del Toro Runzer, Claudia Beatriz
    Paul Armenta-Perez, Vicente
    Pablo Flores-Gutierrez, Juan
    Quintanilla-Guzman, Arturo
    Salinas-Santander, Mauricio
    Francisco Gonzalez-Guerrero, Juan
    Bosques-Padilla, Francisco
    Santos, Arturo
    Guadalupe Martinez-Rodriguez, Herminia
    JOURNAL OF BUON, 2016, 21 (04): : 935 - 940
  • [44] F-19 NUCLEAR MAGNETIC-RESONANCE CHARACTERIZATION OF TERNARY COMPLEXES OF FOLATE DERIVATIVES, 5-FLUORODEOXYURIDYLATE AND LACTOBACILLUS-CASEI THYMIDYLATE SYNTHETASE
    LEWIS, CA
    ELLIS, PD
    DUNLAP, RB
    BIOCHEMISTRY, 1981, 20 (08) : 2275 - 2285
  • [45] Correlation between augmentative effects of leucovorin on 5-fluorouracil and thymidylate synthase inhibition
    Yamada Y.
    Sakata Y.
    Tsushima K.
    Satoh T.
    International Journal of Clinical Oncology, 1997, 2 (1) : 10 - 14
  • [46] Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity
    M-C Etienne
    K Ilc
    J-L Formento
    P Laurent-Puig
    P Formento
    S Cheradame
    J-L Fischel
    G Milano
    British Journal of Cancer, 2004, 90 : 526 - 534
  • [47] INVITRO AND INVIVO INHIBITION OF THYMIDYLATE SYNTHASE OF HUMAN COLON CANCER BY 5-FLUOROURACIL
    PETERS, GJ
    LAURENSSE, EJ
    VANGROENINGEN, CJ
    MEIJER, S
    PINEDO, HM
    PURINE AND PYRIMIDINE METABOLISM IN MAN VI, PT A: CLINICAL AND MOLECULAR BIOLOGY, 1989, 253 : 439 - 445
  • [48] Thymidylate synthase polymorphism and survival of colorectal cancer patients treated with 5-fluorouracil
    Ulrich, CM
    Potter, JD
    BRITISH JOURNAL OF CANCER, 2002, 86 (08) : 1365 - 1365
  • [49] Thymidylate synthase polymorphism and survival of colorectal cancer patients treated with 5-fluorouracil
    C M Ulrich
    J D Potter
    British Journal of Cancer, 2002, 86 : 1365 - 1365
  • [50] Transcriptional regulation of thymidylate synthase as a mechanism of resistance to 5-fluorouracil and tomudex.
    Longley, DB
    Ferguson, PR
    Boyer, J
    Latif, T
    Maxwell, P
    Harkin, DP
    Johnston, PG
    CLINICAL CANCER RESEARCH, 2000, 6 : 4551S - 4551S
12345