N-(INDOL-3-YLGLYOXYLYL)AMINO ACID ESTER DERIVATIVES - SYNTHESIS AND INTERACTION PROPERTIES AT THE BENZODIAZEPINE RECEPTOR

被引：0
|
作者：
PRIMOFIORE, G [1 ]
DASETTIMO, F [1 ]
MARINI, AM [1 ]
LAMOTTA, C [1 ]
MARTINI, C [1 ]
SENATORE, G [1 ]
LUCACCHINI, A [1 ]
机构：
[1] UNIV PISA, IST POLICATTEDRA DISCIPLINE BIOL, I-56126 PISA, ITALY
来源：
FARMACO | 1995年 / 50卷 / 01期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Several N-(indol-3-ylglyoxylyl)alanine and glycine ester derivatives were prepared to evaluate the influence of the ester group size both on affinity and on activity at the benzodiazepine receptor. Moreover, indol-3-ylglyoxylic acid esters, closely related to 3-alkoxy-beta-carbolines, were synthesized and tested in vitro on the benzodiazepine receptor.
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页码：5 / 12
页数：8
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