THE NUCLEOTIDE-SEQUENCE OF THE EQUINE HERPESVIRUS-4 THYMIDINE KINASE GENE

被引：24
|
作者：
NICOLSON, L [1 ]
CULLINANE, AA [1 ]
ONIONS, DE [1 ]
机构：
[1] IRISH EQUINE CTR, NAAS, KILDARE, IRELAND
来源：
JOURNAL OF GENERAL VIROLOGY | 1990年 / 71卷
关键词：
D O I：
10.1099/0022-1317-71-8-1801
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
We have determined the genomic location and nucleotide sequence of the equine herpesvirus 4 thymidine kinase (TK) gene. The gene is positioned at approximately 0.48 map units within the long unique component of the genome and is flanked by genes encoding a herpes simplex virus 1 (HSV-1) UL24 homologue and glycoprotein H. The predicted protein is composed of 352 amino acids, and has an M(r) of 38 800 and exhibits 36% identity to the predicted TK of HSV-1.
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页码：1801 / 1805
页数：5
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