SYNTHESIS AND N-TERMINAL AND C-TERMINAL EXTENSION OF PEPTIDYL ALPHA,ALPHA-DIFLUOROALKYL KETONES

被引：16

作者：

HONG, WP ^{[1
]}

DONG, LW ^{[1
]}

CAI, ZH ^{[1
]}

TITMAS, R ^{[1
]}

机构：

[1] IGEN INC,ROCKVILLE,MD 20852

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)77704-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of the dipeptidyl and tetrapeptidyl-alpha, alpha-difluoroalkyl ketones is described. The key intermediate 6 can be extended at not only the C-terminal but also the N-terminal.

引用

页码：741 / 744

页数：4

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