PAF-ACETHER IN HUMAN SKIN

被引：0
|
作者：
DENIZOT, Y
MICHEL, L
BENVENISTE, J
MEYBECK, A
THOMAS, Y
DUBERTRET, L
机构：
[1] INSERM,U200,32 RUE CARNETS,F-92140 CLAMART,FRANCE
[2] INSERM,U312,F-92010 CRETEIL,FRANCE
[3] LVMH RECH,F-92704 COLOMBES,FRANCE
来源：
LIPIDS | 1991年 / 26卷 / 12期
关键词：
D O I：
10.1007/BF02536508
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Paf is a phospholipid mediator present in human skin which induces inflammatory events, such as neutrophil infiltration and increased vascular permeability. Recent data suggest that cutaneous cells, such as fibroblasts and keratinocytes, produce paf and that paf is released during allergic cutaneous reactions. It is tempting to speculate that paf may contribute to the development of various skin disorders with acute and chronic skin inflammation. Paf antagonists may help in bringing answers to this hypothesis and may offer new prospects for the treatment of cutaneous inflammatory diseases.
引用
收藏
页码：1093 / 1094
页数：2
相关论文
共 50 条
  • [21] EXPERIMENTAL PRURITUS EVOKED BY PLATELET ACTIVATING FACTOR (PAF-ACETHER) IN HUMAN-SKIN
    FJELLNER, B
    HAGERMARK, O
    [J]. ACTA DERMATO-VENEREOLOGICA, 1985, 65 (05) : 409 - 412
  • [22] STUDY OF THE EFFECTS OF PAF-ACETHER ON HUMAN NASAL AIRWAYS
    LEGGIERI, E
    TEDESCHI, A
    LORINI, M
    BIANCO, A
    MIADONNA, A
    [J]. ALLERGY, 1991, 46 (06) : 466 - 471
  • [23] PERMEABILITY-INCREASING ABILITY OF PAF-ACETHER IN RAT SKIN
    GERDIN, B
    LUNDBERG, C
    SMEDEGARD, G
    [J]. INFLAMMATION, 1985, 9 (01) : 107 - 112
  • [24] INFLUENCE OF PAF-ACETHER ON LECITHIN-ORIENTED MULTIBILAYERS MONITORED BY ESR - INTERACTION OF PAF-ACETHER WITH CHOLESTEROL
    OLIVIER, JL
    CHACHATY, C
    WOLF, C
    BEREZIAT, G
    [J]. BIOCHIMIE, 1989, 71 (01) : 105 - 109
  • [25] PRODUCTION OF PAF-ACETHER BY HUMAN EPIDERMAL-CELLS
    MICHEL, L
    DENIZOT, Y
    THOMAS, Y
    JEANLOUIS, F
    HESLAN, M
    BENVENISTE, J
    DUBERTRET, L
    [J]. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1990, 95 (05) : 576 - 581
  • [26] PRESENCE OF PAF-ACETHER IN RHEUMATIC DISEASES
    HILLIQUIN, P
    MENKES, CJ
    LAOUSSADI, S
    BENVENISTE, J
    ARNOUX, B
    [J]. ANNALS OF THE RHEUMATIC DISEASES, 1992, 51 (01) : 29 - 31
  • [27] MEDIATORS OF THE RENAL ACTIONS OF PAF-ACETHER
    HEBERT, RL
    BRAQUET, P
    SIROIS, P
    PLANTE, GE
    [J]. KIDNEY INTERNATIONAL, 1987, 31 (01) : 271 - 271
  • [28] BIOSYNTHESIS OF PAF-ACETHER .16. ACETYLTRANSFERASE SPECIFICITY DETERMINES COMPOSITION OF PAF-ACETHER MOLECULAR-SPECIES IN HUMAN POLYMORPHONUCLEAR NEUTROPHILS
    NINIO, E
    BESSOU, G
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1085 (01) : 136 - 139
  • [29] PHARMACOLOGICAL PROPERTIES AND INHIBITION OF PAF-ACETHER
    VARGAFTIG, BB
    ROTILIO, D
    LEFORT, J
    FOUQUE, F
    MEDEIROS, MC
    WAL, F
    [J]. THROMBOSIS AND HAEMOSTASIS, 1983, 50 (01) : 174 - 174
  • [30] PAF-ACETHER IN NECROTIZING ENTEROCOLITIS - REPLY
    ISRAEL, EJ
    [J]. GASTROENTEROLOGY, 1992, 102 (03) : 1092 - 1092
12345