AN ASSAY FOR COMPLEMENT FACTOR-B IN SPECIES AT DIFFERENT LEVELS OF EVOLUTION

被引：4
|
作者：
JENSEN, LB
KOCH, C
机构：
来源：
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY | 1991年 / 15卷 / 03期
关键词：
COMPLEMENT FACTOR-B; EVOLUTION; C3; CONVERTASE;
D O I：
10.1016/0145-305X(91)90008-M
中图分类号：
S9 [水产、渔业];
学科分类号：
0908 ;
摘要：
The alternative complement pathway is regarded as the evolutionary ancestral complement system. It is therefore of interest to analyze and characterize factor B of the alternative complement pathway in animals at different levels of evolution. We describe a functional assay which is based on the interaction of factor B from various animal species with Cobra Venom Factor, the snake C3b-analog. The signal system in the assay is C3-conversion in factor B-depleted chicken serum. The results show that a functional C3-convertase can be created with factor B from mammals, aves, and amphibians.
引用
收藏
页码：173 / 179
页数：7
相关论文
共 50 条
  • [1] CLONING AND SEQUENCING OF THE PORCINE COMPLEMENT FACTOR-B
    PEELMAN, LJ
    VANDEWEGHE, AR
    COPPIETERS, WR
    VANZEVEREN, AJ
    BOUQUET, YH
    IMMUNOGENETICS, 1991, 34 (03) : 192 - 195
  • [2] NOMENCLATURE FOR HUMAN-COMPLEMENT FACTOR-B
    KAZATCHKINE, MD
    GESERICK, G
    ABBAL, M
    ALPER, CA
    BERTRAMS, J
    DUTOIT, E
    HAUPTMANN, G
    LOKKI, ML
    MAUFF, G
    NAKAMURA, S
    SEGURADO, OG
    SIEMENS, I
    SUZUKI, K
    WEIDINGER, S
    EUROPEAN JOURNAL OF IMMUNOGENETICS, 1993, 20 (04): : 307 - 309
  • [3] DNA METHYLATION AND THE ORIGIN OF COMPLEMENT FACTOR-B POLYMORPHISM
    MEJIA, JE
    JAHN, I
    HAUPTMANN, G
    HUMAN IMMUNOLOGY, 1995, 42 (03) : 241 - 244
  • [4] ACTIVATION OF THE ALTERNATIVE PATHWAY OF COMPLEMENT BY ANTISERUM TO FACTOR-B
    WILSON, MR
    ARROYAVE, CM
    TAN, EM
    JOURNAL OF LABORATORY AND CLINICAL MEDICINE, 1979, 93 (03): : 493 - 498
  • [5] COMPLEMENT FACTOR-B - A NOVEL CLASS OF SERINE PROTEASE
    MOLE, JE
    NIEMANN, MA
    FEDERATION PROCEEDINGS, 1980, 39 (06) : 1997 - 1997
  • [6] QUANTITATIVE DIFFERENCES BETWEEN COMPLEMENT FACTOR-B PHENOTYPES
    MORTENSEN, JP
    LAMM, LU
    IMMUNOLOGY, 1981, 42 (04) : 505 - 511
  • [7] COMPLEMENT FACTOR-B ALLOTYPES AND AUTOIMMUNE BULLOUS DERMATOSIS
    DOUTRE, MS
    BEYLOT, C
    ABBAL, M
    ANNALES DE DERMATOLOGIE ET DE VENEREOLOGIE, 1987, 114 (04): : 638 - 638
  • [8] STRUCTURE AND FUNCTION OF FACTOR-B OF THE ALTERNATIVE COMPLEMENT PATHWAY
    MOLE, JE
    ANDERSON, JK
    ABRAHAM, N
    BHOWN, AS
    FEDERATION PROCEEDINGS, 1981, 40 (03) : 962 - 962
  • [9] FACTOR-B OF ALTERNATIVE COMPLEMENT PATHWAY ON HUMAN LYMPHOCYTES
    HALBWACHS, L
    LACHMANN, PJ
    SCANDINAVIAN JOURNAL OF IMMUNOLOGY, 1976, 5 (6-7) : 697 - 704
  • [10] A NEW TAQI POLYMORPHISM OF THE COMPLEMENT FACTOR-B GENE
    LOBACCARO, JM
    GHANEM, N
    SULTAN, C
    LEFRANC, G
    NUCLEIC ACIDS RESEARCH, 1988, 16 (24) : 11851 - 11851
12345