SYNTHESIS OF 1,4-DIHYDROPYRIDINES UNDER MICROWAVE IRRADIATION

被引：76
|
作者：
ALAJARIN, R [1 ]
VAQUERO, JJ [1 ]
NAVIO, JLG [1 ]
ALVAREZBUILLA, J [1 ]
机构：
[1] UNIV ALCALA DE HENARES, DEPT QUIM ORGAN, E-28871 ALCALA DE HENARES, SPAIN
来源：
SYNLETT | 1992年 / 04期
关键词：
D O I：
10.1055/s-1992-21345
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A domestic microwave oven has been used to accelerate the Hantzsch synthesis of dialkyl 4-aryl-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylates 1 and a variant leading to 4,4-dialkyl-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarbonitriles 2. In comparison with the traditional reflux method, similar or higher yields were obtained.
引用
收藏
页码：297 / 298
页数：2
相关论文
共 50 条
  • [31] Hydrogen transfer from Hantzsch 1,4-dihydropyridines to carbon-carbon double bonds under microwave irradiation
    Torchy, S
    Cordonnier, G
    Barbry, D
    Vanden Eynde, JJ
    MOLECULES, 2002, 7 (07) : 528 - 533
  • [32] DIHYDROPYRIDINES .2. SYNTHESIS OF 1,4-DIHYDROPYRIDINES WITH BRIDGEHEAD NITROGEN
    MEYER, H
    BOSSERT, F
    HORSTMANN, H
    JUSTUS LIEBIGS ANNALEN DER CHEMIE, 1977, (11-1): : 1888 - 1894
  • [33] A novel micro-flow system under microwave irradiation for continuous synthesis of 1,4-dihydropyridines in the absence of solvents via Hantzsch reaction
    He, Wei
    Fang, Zheng
    Zhang, Kai
    Tu, Tao
    Lv, Niuniu
    Qiu, Chuanhong
    Guo, Kai
    CHEMICAL ENGINEERING JOURNAL, 2018, 331 : 161 - 168
  • [34] An Efficient Procedure for the Synthesis of Hantzsch 1,4-Dihydropyridines Under Mild Conditions
    Ghorbani-Choghamarani, Arash
    Zolfigol, Mohammad Ali
    Salehi, Peyman
    Ghaemi, Ezat
    Madrakian, Elaheh
    Nasr-Isfahani, Hossein
    Shahamirian, Mozhjgan
    ACTA CHIMICA SLOVENICA, 2008, 55 (03) : 644 - 647
  • [35] Iodocyclization of 1,4-dihydropyridines
    Lavilla, R
    Coll, O
    Nicolàs, M
    Bosch, J
    TETRAHEDRON LETTERS, 1998, 39 (28) : 5089 - 5092
  • [36] Unprecedented synthesis of hantzsch 1,4-dihydropyridines under biginelli reaction conditions
    Yadav, JS
    Reddy, BVS
    Reddy, PT
    SYNTHETIC COMMUNICATIONS, 2001, 31 (03) : 425 - 430
  • [37] PHOTOOXIDATION OF 1,4-DIHYDROPYRIDINES
    MITSUNOBU, O
    WADA, M
    MASUDA, H
    MATSUMOT.S
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1972, 45 (05) : 1453 - +
  • [38] REACTIONS OF 1,4-DIHYDROPYRIDINES
    SAUSINSH, A
    DUBUR, G
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1993, (05): : 579 - 612
  • [39] OXIDATION OF 1,4-DIHYDROPYRIDINES
    DUBUR, GY
    ULDRIKIS, YR
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1970, (01): : 83 - &
  • [40] SYNTHESIS AND PROPERTIES OF SOME SIMPLE 1,4-DIHYDROPYRIDINES
    KOSOWER, EM
    SORENSEN, TS
    JOURNAL OF ORGANIC CHEMISTRY, 1962, 27 (11): : 3764 - &
12345