SYNTHESIS OF 1,4-DIHYDROPYRIDINES UNDER MICROWAVE IRRADIATION

被引：76
|
作者：
ALAJARIN, R [1 ]
VAQUERO, JJ [1 ]
NAVIO, JLG [1 ]
ALVAREZBUILLA, J [1 ]
机构：
[1] UNIV ALCALA DE HENARES, DEPT QUIM ORGAN, E-28871 ALCALA DE HENARES, SPAIN
来源：
SYNLETT | 1992年 / 04期
关键词：
D O I：
10.1055/s-1992-21345
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A domestic microwave oven has been used to accelerate the Hantzsch synthesis of dialkyl 4-aryl-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylates 1 and a variant leading to 4,4-dialkyl-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarbonitriles 2. In comparison with the traditional reflux method, similar or higher yields were obtained.
引用
收藏
页码：297 / 298
页数：2
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