PHOSPHINOARYLOXAZOLINES AND PHOSPHINOALKYLOXAZOLINES AS NEW CHIRAL LIGANDS FOR ENANTIOSELECTIVE CATALYSIS - VERY HIGH ENANTIOSELECTIVITY IN PALLADIUM CATALYZED ALLYLIC SUBSTITUTIONS

被引：592
|
作者：
SPRINZ, J [1 ]
HELMCHEN, G [1 ]
机构：
[1] UNIV HEIDELBERG,INST ORGAN CHEM,IM NEUENHEIMER FELD 270,W-6900 HEIDELBERG,GERMANY
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 11期
关键词：
D O I：
10.1016/S0040-4039(00)60774-8
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Chiral phosphinoaryl- and phosphinoalkyloxazolines, a new class of chelate ligands, were prepared via convenient routes. Palladium complexes of the new ligands have proved to be highly effective catalysts for allylic substitution reactions. Enantioselectivity of up to 98.5 % ee in the reaction of dimethyl malonate with 1,3-diphenyl-2-propenyl acetate is the highest so far achieved in this area.
引用
收藏
页码：1769 / 1772
页数：4
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