ANATOMICAL AND FUNCTIONAL CORRELATES OF COGNITIVE DEFICIT IN MULTIPLE-SCLEROSIS

被引：6
|
作者：
POZZILLI, C
GASPERINI, C
ANZINI, A
GRASSO, MG
RISTORI, G
FIESCHI, C
机构：
[1] Department of Neurological Science, University of Rome La Sapienza, Rome
来源：
JOURNAL OF THE NEUROLOGICAL SCIENCES | 1993年 / 115卷
关键词：
MULTIPLE SCLEROSIS; COGNITIVE DEFICIT; MAGNETIC RESONANCE IMAGING (MRI); POSITRON EMISSION TOMOGRAPHY (PET); SINGLE PHOTON EMISSION TOMOGRAPHY (SPET);
D O I：
10.1016/0022-510X(93)90210-P
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
This brief article reviews the present state of knowledge concerning the relationship between structural and functional cerebral abnormalities and the cognitive deficits associated with multiple sclerosis. Currently available neuroimaging techniques have substantially contributed to a better understanding of the latter, suggesting that cortical-subcortical disconnection is the most likely cause of the cognitive disturbance. Longitudinal studies are needed to determine the natural history of the cognitive deficit and its relationship to the cerebral changes detected by neuroimaging techniques.
引用
收藏
页码：S55 / S58
页数：4
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