USE OF IN-VITRO METHODOLOGY TO PREDICT THE IRRITANCY POTENTIAL OF SURFACTANTS

被引：18
|
作者：
HUBBARD, AW [1 ]
MOORE, LJ [1 ]
CLOTHIER, RH [1 ]
SULLEY, H [1 ]
ROLLIN, KA [1 ]
机构：
[1] UNIV NOTTINGHAM,DEPT HUMAN MORPHOL,FRAME ALTERNAT LAB,NOTTINGHAM NG7 2UH,ENGLAND
来源：
TOXICOLOGY IN VITRO | 1994年 / 8卷 / 04期
关键词：
D O I：
10.1016/0887-2333(94)90044-2
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
A battery of confirmatory and complementary in vitro assays was used to investigate a series of surfactants with different irritancy potentials, as confirmed by human skin patch testing. This was found to distinguish between sodium lauryl sulfate and its analogues, and when further tested on formulations the battery of assays was again capable of predicting the human data.
引用
收藏
页码：689 / 691
页数：3
相关论文
共 50 条
  • [41] ANTIOXIDANT POTENTIAL OF PHLOROGLUCINOL; AN IN-VITRO APPROACH
    Archana, I.
    Vijayalakshmi, K.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, 9 (07): : 2947 - 2951
  • [42] CONTACT POTENTIAL DIFFERENCE OF CELLS IN-VITRO
    MINC, S
    DOLOWY, K
    BIOPHYSIK, 1973, 9 (02): : 172 - 176
  • [43] METHODOLOGY IN-VITRO OF INTESTINAL TRACE-ELEMENT ABSORPTION
    SCHWARZ, FJ
    KIRCHGESSNER, M
    INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH, 1972, 42 (03) : 497 - +
  • [44] A MICROSURGICAL METHODOLOGY FOR HUMAN CELLS IN-VITRO - EVOLUTION AND APPLICATIONS
    DIACUMAKOS, EG
    HOLLAND, S
    PECORA, P
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1970, 65 (04) : 911 - +
  • [45] An Experimental Methodology For The Analysis Of The Headspace Of In-Vitro Culture Cells
    Santonico, M.
    Pennazza, G.
    Bartolazzi, A.
    Martinelli, E.
    Paolesse, R.
    Di Natale, C.
    D'Amico, A.
    OLFACTION AND ELECTRONIC NOSE, PROCEEDINGS, 2009, 1137 : 427 - +
  • [46] Evaluating the sensitization potential of surfactants: How do surfactants behave in in vitro methods
    Mehling, A.
    Ball, N.
    Carrillo, J.
    Eigler, D.
    Garcia, C.
    Graham, C.
    Haux, C.
    Natsch, A.
    TOXICOLOGY LETTERS, 2011, 205 : S153 - S153
  • [47] COLLAGEN FIBRILLOGENESIS IN-VITRO - ACCELERATIVE EFFECT OF SURFACTANTS ON COLLAGEN FIBRIL FORMATION
    HONYA, M
    MIZUNUMA, H
    JOURNAL OF BIOCHEMISTRY, 1974, 75 (01): : 113 - 121
  • [48] MICROEMULSIONS WITH SUCROSE FATTY ESTER SURFACTANTS .1. IN-VITRO CHARACTERIZATION
    KEIPERT, S
    SCHULZ, G
    PHARMAZIE, 1994, 49 (2-3): : 195 - 197
  • [49] USE OF HUMAN SKIN RECOMBINANTS AS AN IN-VITRO MODEL FOR TESTING THE IRRITATION POTENTIAL OF CUTANEOUS IRRITANTS
    PONEC, M
    KEMPENAAR, J
    SKIN PHARMACOLOGY, 1995, 8 (1-2): : 49 - 59
  • [50] The potential use of in-vitro maturation of germinal vesicle-stage oocytes in low responders
    Requena, A
    Neuspiller, F
    Cobo, AC
    Aragonés, M
    Ruíz, A
    Remohí, J
    Simón, C
    Pellicer, A
    HUMAN REPRODUCTION, 1998, 13 : 23 - 23
12345