GENETIC-HETEROGENEITY OF EARLY-ONSET FAMILIAL BREAST-CANCER

被引：0
|
作者：
SOBOL, H
MAZOYER, S
NAROD, SA
SMITH, SA
BLACK, DM
KERBRAT, P
JAMOT, B
SOLOMON, E
PONDER, BAJ
GUERIN, D
机构：
[1] MCGILL UNIV,DIV MED GENET,MONTREAL H3A 2T5,QUEBEC,CANADA
[2] UNIV CAMBRIDGE,DEPT PATHOL,CAMBRIDGE,ENGLAND
[3] IMPERIAL CANC RES FUND,SOMAT CELL GENET,LONDON WC2A 3PX,ENGLAND
[4] CTR EUGENE MARQUIS,DEPT MED,RENNES,FRANCE
来源：
HUMAN GENETICS | 1992年 / 89卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
A gene for early-onset familial breast cancer has recently been mapped to the chromosome 17q12-23 region. In order to confirm the gene location. we have tested an extensive early-onset breast cancer family with 4 markers in this chromosome region. Linkage was negative with all 4 markers. This study suggests that there is genetic heterogeneity among early-onset breast cancer families.
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页码：381 / 383
页数：3
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