SYNTHESIS OF 3-(1,2,3,6-TETRAHYDRO PYRIDIN-4-YL) 1H-INDOLES AND STUDY OF THEIR SEROTONINERGIC AND ANTIDOPAMINERGIC PROPERTIES

被引：45
|
作者：
GUILLAUME, J [1 ]
DUMONT, C [1 ]
LAURENT, J [1 ]
NEDELEC, L [1 ]
机构：
[1] ROUSSEL UCLAF,CTR RECH,102 ROUTE NOISY,F-93230 ROMAINVILLE,FRANCE
来源：
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 22卷 / 01期
关键词：
D O I：
10.1016/0223-5234(87)90172-3
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：33 / 43
页数：11
相关论文
共 50 条
  • [1] SYNTHESIS AND FUNCTIONALIZATION OF THE 3-(1,3,4-OXADIAZOL-2-YL)-1H-INDOLES
    Alyab'ev, S. B.
    Kravchenko, D. V.
    Ivashchenko, A. V.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2009, 45 (10) : 1270 - 1275
  • [2] Synthesis and functionalization of the 3-(1,3,4-oxadiazol-2-yl)-1h-indoles
    S. B. Alyab’ev
    D. V. Kravchenko
    A. V. Ivashchenko
    Chemistry of Heterocyclic Compounds, 2009, 45 : 1270 - 1275
  • [3] Efficient synthesis of 3-(4,5-dihydro-1H-imidazole-2-yl)-1H-indoles
    Hary, U
    Roettig, U
    Paal, R
    TETRAHEDRON LETTERS, 2001, 42 (31) : 5187 - 5189
  • [4] Synthesis and biological evaluation of 3-(azolylmethyl)-1H-indoles and 3-(α-azolylbenzyl)-1H-indoles as selective aromatase inhibitors
    Le Borgne, Marc
    Marchand, Pascal
    Nourrisson, Marie-Renee
    Loquet, Denis
    Palzer, Martina
    Le Baut, Guillaume
    Hartmann, Rolf W.
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2007, 22 (05) : 667 - 676
  • [5] Hexafluoroisopropanol/trifluoromethanesulfonic acid assists the synthesis of 3-(2-chloropyrimidin-4-yl)-1H-indoles
    Liu, Shuai
    Pan, Fang Xia
    Qi, Yu
    Bai, Hai Yun
    TETRAHEDRON, 2023, 146
  • [6] An Improved Synthesis of 1-(1,2,3,6-Tetrahydro-1-methyl-4-pyridin yl)ethanone, Isoarecolone
    Beach, J. W.
    Journal of Heterocyclic Chemistry, 34 (06):
  • [7] A NEW, FACILE SYNTHESIS OF 3-(1-DIALKYLAMINOALKYL)-1H-INDOLES
    MORIYA, T
    HAGIO, K
    YONEDA, N
    SYNTHESIS-STUTTGART, 1980, (09): : 728 - 730
  • [8] Synthesis of Benzocyclohepta[b]indoles by Lewis Acid Catalyzed Annulation of Two 3-(1H-Isochromen-1-yl)-1H-indoles
    Xie, Ye-Xiang
    Tang, Ri-Yuan
    Song, Ren-Jie
    Xiang, Jian-Nan
    Li, Jin-Heng
    JOURNAL OF ORGANIC CHEMISTRY, 2014, 79 (02): : 686 - 691
  • [9] Synthesis of new 3-(trifluoromethyl)-1H-indoles by reduction of trifluoromethyloxoindoles
    Bastos, Monica M.
    Mayer, Lucia M. U.
    Figueira, Elza C. S.
    Soares, Marcio
    Kover, Warner B.
    Boechat, Nubia
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2008, 45 (04) : 969 - 973
  • [10] ZnII and CuII complexes generated from 5-(pyridin-4-yl)-3-[2-(pyridin-4-yl)ethyl]-1,3,4-oxadiazole-2(3H)-thione
    Zhao, Hang-Ju
    Ma, Jian-Ping
    Liu, Qi-Kui
    Dong, Yu-Bin
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 2013, 69 : 716 - +
12345