TLC-SCREENING OF IMPORTANT PHARMACEUTICAL SUBSTANCES USING FLUORESCENCE DETECTION

被引：10
|
作者：
ROCHHOLZ, G [1 ]
MAYR, A [1 ]
SCHUTZ, H [1 ]
机构：
[1] UNIV GIESSEN,INST LEGAL MED,FRANKFURTER STR 58,W-6300 GIESSEN,GERMANY
来源：
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY | 1993年 / 346卷 / 6-9期
关键词：
D O I：
10.1007/BF00321297
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
Observation of fluorescence reactions on TLC plates is a valuable additional tool within the scope of screening procedures for many toxicologically relevant substances commonly encountered in clinical- and forensic-toxicological analysis. The reactions are based on native fluorescence without any treatment and on reactions obtained with an approved derivatization procedure. Due to the enorinous sensitivity of the fluorescence detection, the method is also applicable to very low concentrations and small amounts of biological materials. The procedures described in this article have proven their high pragmatic usefulness in many practical cases.
引用
收藏
页码：819 / 827
页数：9
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