AMINO-ACIDS AND PEPTIDES .80. STEREOSELECTIVE SYNTHESES OF THE ANTIBIOTICS (+)-NEGAMYCIN AND (-)-HON (RI-331)

被引：0

作者：

SCHMIDT, U

STABLER, F

LIEBERKNECHT, A

机构：

来源：

SYNTHESIS-STUTTGART | 1992年 / 05期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereoselective syntheses of the antibiotics (-)-HON (5-hydroxy-4-OXO-L-norvaline, RI-331) and (+)-negamycin starting from (S)-4-[(Z)-2-(benzyloxycarbonylamino)-2-(tert-butoxycar-bonyl)vinyl]-2,2-dimethyl-1,3-dioxolane and (R)-3-benzyloxycar-bonyl-5-[(Z)-2-(tert-butoxycarbonylamino)-2-(methoxycarbonyl) vinyl]-2,2-dimethyl-1,3-oxazolidine, respectively, are described.

引用

页码：482 / 486

页数：5

共 35 条

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