AN ION-STORAGE TIME-OF-FLIGHT MASS-SPECTROMETER FOR ANALYSIS OF ELECTROSPRAY IONS

被引：32
|
作者：
BOYLE, JG [1 ]
WHITEHOUSE, CM [1 ]
FENN, JB [1 ]
机构：
[1] YALE UNIV,DEPT CHEM ENGN,NEW HAVEN,CT 06520
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1991年 / 5卷 / 09期
关键词：
D O I：
10.1002/rcm.1290050906
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A preliminary design and implementation of a novel approach to electrospray-mass spectrometry are described. Based on a time-of-flight mass analysis, the instrument provides several important advantages for on-line mass analysis: 1, simplicity, ease of use and low manufacturing cost; 2, rapid scan speed, yielding quasi-instantaneous full mass scans at repetition rates up to several kHz; 3, soft ionization and accurate mass determination of extremely large analyte molecules; 4, high sensitivity.
引用
收藏
页码：400 / 405
页数：6
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