STIMULATORY ACTION OF CALCIUM L-THREONATE ON ASCORBIC-ACID UPTAKE BY A HUMAN T-LYMPHOMA CELL-LINE

被引：22
|
作者：
FAY, MJ [1 ]
VERLANGIERI, AJ [1 ]
机构：
[1] UNIV MISSISSIPPI,SCH PHARM,DEPT PHARMACOL,UNIVERSITY,MS 38677
来源：
LIFE SCIENCES | 1991年 / 49卷 / 19期
关键词：
D O I：
10.1016/0024-3205(91)90388-R
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
The effects of preincubation of human T-lymphoma cells with increasing concentrations of calcium L-threonate on the uptake of L-[1-C-14]ascorbic acid were examined. Calcium L-threonate (0 - 1,000 mg%) stimulated ascorbic acid (1.25 mg%) uptake in a dose-dependent manner. These results indicate that calcium threonate and possibly other ascorbic acid metabolites have biological activity and potential pharmacological applications.
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页码：1377 / 1381
页数：5
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