Synthesis of 5-alkoxy-4-alkylamino-1,2-benzoquinones

被引：0
|
作者：
Viallon, L
Reinaud, O
Capdevielle, P
Maumy, M
机构：
来源：
SYNTHESIS-STUTTGART | 1995年 / 12期
关键词：
1,2-benzoquinones; aminoquinones; nucleophilic substitution by amines; regioselectivity;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A simple and efficient method is described for a general synthesis of 4-dialkylamino-5-methoxy-1,2-benzoquinones 3 which involves, in polar solvents, a regioselective (> 95 %) nucleophilic monosubstitution by a wide range of secondary aliphatic amines on an easily prepared 1,2-quinone 1. Regioselectivity is not observed in the reaction of primary amines with 1, but a further reaction with an alcohol in basic medium allows valorization of the undesirable product.
引用
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页码：1534 / +
页数：1
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