PARACOCCIDIOIDES BRASILIENSIS-STIMULATED HUMAN GAMMA/DELTA T-CELLS SUPPORT ANTIBODY-PRODUCTION BY B-CELLS

被引：13
|
作者：
MUNK, ME
FAZIOLI, RA
CALICH, VLG
KAUFMANN, SHE
机构：
[1] UNIV SAO PAULO,DEPT IMMUNOL,BR-05508 SAO PAULO,BRAZIL
[2] ADOLFO LUTZ INST,DEPT IMMUNOL,BR-01246 SAO PAULO,BRAZIL
来源：
INFECTION AND IMMUNITY | 1995年 / 63卷 / 04期
关键词：
D O I：
10.1128/IAI.63.4.1608-1610.1995
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Paracoccidioidomycosis patients show hyperactive humoral immune responses. Consequently, we investigated whether cytokines in supernatants from Paracoccidioides brasiliensis-stimulated gamma/delta T cells support B-cell activation. We detected proliferation of B cells and increased immunoglobulin M (IgM) and IgG production. Thus, gamma/delta T cells may participate in polyclonal B-cell activation during paracoccidioidomycosis.
引用
收藏
页码：1608 / 1610
页数：3
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