PRECLINICAL AND CLINICAL-EVALUATION OF RECOMBINANT HUMAN MACROPHAGE COLONY-STIMULATING FACTOR (RHM-CSF)

被引：23
|
作者：
GARNICK, MB [1 ]
STOUDEMIRE, JB [1 ]
机构：
[1] HARVARD UNIV,SCH MED,DANA FARBER CANC INST,BOSTON,MA 02115
来源：
INTERNATIONAL JOURNAL OF CELL CLONING | 1990年 / 8卷
关键词：
Hematopoietic growth factors; Recombinant human macrophage colony‐stimulating factor;
D O I：
10.1002/stem.5530080733
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The promise of hematopoietic growth factors is now being realized as clinical trials become more mature. The uses of granulocyte‐macrophage colony‐stimulating factor and granulocyte colony‐stimulating factor are now becoming more established in therapeutic applications of disease states. A variety of new hematopoietic growth factors is on the horizon, including recombinant human macrophage colony‐stimulating factor (rhM‐CSF), which has recently entered clinical trials after extensive preclinical testing. The diverse biological actions of rhM‐CSF will provide novel ways of approaching various medical problems across the disciplines of hematology, oncology, infectious disease and cardiology. Copyright © 1990 AlphaMed Press
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页码：356 / 373
页数：18
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