PRECLINICAL AND CLINICAL-EVALUATION OF RECOMBINANT HUMAN MACROPHAGE COLONY-STIMULATING FACTOR (RHM-CSF)

被引：23

作者：

GARNICK, MB ^{[1
]}

STOUDEMIRE, JB ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,DANA FARBER CANC INST,BOSTON,MA 02115

来源：

INTERNATIONAL JOURNAL OF CELL CLONING | 1990年 / 8卷

关键词：

Hematopoietic growth factors; Recombinant human macrophage colony‐stimulating factor;

D O I：

10.1002/stem.5530080733

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The promise of hematopoietic growth factors is now being realized as clinical trials become more mature. The uses of granulocyte‐macrophage colony‐stimulating factor and granulocyte colony‐stimulating factor are now becoming more established in therapeutic applications of disease states. A variety of new hematopoietic growth factors is on the horizon, including recombinant human macrophage colony‐stimulating factor (rhM‐CSF), which has recently entered clinical trials after extensive preclinical testing. The diverse biological actions of rhM‐CSF will provide novel ways of approaching various medical problems across the disciplines of hematology, oncology, infectious disease and cardiology. Copyright © 1990 AlphaMed Press

引用

下载

页码：356 / 373

页数：18

共 50 条

[1] Recombinant human macrophage colony-stimulating factor (rhM-CSF) induced thrombocytopenia (TCP) in dogs.
Abrams, K
Yunusov, MY
Slichter, SJ
Moore, P
Nelp, WB
Burstein, SA
McDonough, S
Durack, LD
Storer, B
Storb, R
Gass, MJ
Georges, G
Nash, RA
BLOOD, 2002, 100 (11) : 406A - 406A
[2] RECOMBINANT HUMAN MACROPHAGE-COLONY-STIMULATING FACTOR (RHM-CSF) DOES NOT ENHANCE POSTANGIOPLASTY RESTENOSIS
MASON, L
KEANEY, J
VITA, J
HAYES, L
FERRANTI, T
CLINTON, S
LOSCALZO, J
SCHAUB, R
FASEB JOURNAL, 1994, 8 (04): : A318 - A318
[3] EFFECTS OF RECOMBINANT HUMAN MACROPHAGE-COLONY-STIMULATING FACTOR (RHM-CSF) ON CHOLESTEROL LEVELS IN HEALTHY-VOLUNTEERS
SHERMAN, ML
KAYE, JA
SCHINDLER, J
FAULKNER, R
SCHAUB, RG
TUBRIDY, KL
KUCA, B
GARNICK, MB
BLOOD, 1993, 82 (10) : A235 - A235
[4] Selective biochemical modification of functional residues in recombinant human macrophage colony-stimulating factor beta (rhM-CSF beta): Identification by mass spectrometry
Glocker, MO
Kalkum, M
Yamamoto, R
Schreurs, J
BIOCHEMISTRY, 1996, 35 (46) : 14625 - 14633
[5] RECOMBINANT HUMAN MACROPHAGE-COLONY - STIMULATING FACTOR (RHM-CSF) IN NONHUMAN-PRIMATES - SELECTIVE EXPANSION OF A NOVEL MONOCYTE SUBSET
MUNN, DH
BEALL, AC
SABIO, H
TSAI, JF
MARTINEZ, JE
KAVIANI, MD
SCHAUB, RG
GOLDMAN, SJ
BREE, AG
BLOOD, 1993, 82 (10) : A234 - A234
[6] RECOMBINANT HUMAN MACROPHAGE COLONY STIMULATING FACTOR (RHM-CSF) INDUCES AND MAINTAINS CHOLESTEROL LOWERING DURING CONTINOUS ADMINISTRATION INTO THE WHHL RABBIT
BREE, M
SCHAUB, RG
FASEB JOURNAL, 1991, 5 (04): : A726 - A726
[7] Protective effect of mucosal administration of recombinant human macrophage colony stimulating factor (rhM-CSF) on mucosal infection of Sendai virus in mice
Matsuzawa, K
Yoo, YC
Fukushima, A
Yoshimatsu, K
Arikawa, J
Azuma, I
VACCINE, 1997, 15 (01) : 85 - 89
[8] CLINICAL-EXPERIENCE WITH RECOMBINANT HUMAN GRANULOCYTE COLONY-STIMULATING FACTOR AND GRANULOCYTE MACROPHAGE COLONY-STIMULATING FACTOR
MORSTYN, G
LIESCHKE, GJ
SHERIDAN, W
LAYTON, J
CEBON, J
FOX, RM
SEMINARS IN HEMATOLOGY, 1989, 26 (02) : 9 - 13
[9] Characterization of the folding pathway of recombinant human macrophage-colony stimulating-factor β (rhM-CSF β) by bis-cysteinyl modification and mass spectrometry
Happersberger, HP
Stapleton, J
Cowgill, C
Glocker, MO
PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1998, : 50 - 62
[10] RECOMBINANT HUMAN MACROPHAGE COLONY STIMULATING FACTOR (RHM-CSF) REDUCES PLASMA-CHOLESTEROL AND CARRAGEENAN GRANULOMA FOAM CELL-FORMATION IN WHHL RABBITS
HAYES, L
BREE, M
SCHAUB, RG
FASEB JOURNAL, 1991, 5 (04): : A727 - A727

← 1 2 3 4 5 →