USE OF SCANNING ELECTRON-MICROSCOPY IN THE STUDY OF NEPHROTOXIN-INDUCED RENAL PROXIMAL TUBULAR DAMAGE IN-VITRO

被引:0
|
作者
REES, JA
EVANS, JG
BLACKMORE, M
SPENCER, AJ
GRAY, TJB
机构
[1] Sterling Winthrop Pharmaceuticals Research Division, Alnwick, Northumberland NE66 2JH, Willowburn Avenue
关键词
D O I
10.1016/0887-2333(94)90026-4
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Scanning electron microscopy was used to study cephaloridine and gentamicin-induced renal cell injury in vitro. Exposure of renal proximal tubular cells to these toxicants produced changes in cell surface morphology that occurred at concentrations similar to (or below) those affecting neutral red uptake or monolayer permeability.
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页码:601 / 603
页数:3
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