THE 5' REGION OF THE HUMAN THYROGLOBULIN GENE CONTAINS MEMBERS OF THE ALU FAMILY

被引：8
|
作者：
TARGOVNIK, H
PAZ, C
CORACH, D
CHRISTOPHE, D
机构：
[1] UNIV BUENOS AIRES, FAC FARM & BIOQUIM, CATEDRA GENET & BIOL MOLEC, BUENOS AIRES, ARGENTINA
[2] UNIV LIBRE BRUXELLES, INST RECH INTERDISCIPLINAIRE, B-1050 BRUSSELS, BELGIUM
来源：
THYROID | 1992年 / 2卷 / 04期
关键词：
D O I：
10.1089/thy.1992.2.321
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Repeated sequences were identified in the 5' region of the human Tg gene in introns 4, 5, 10, and 11. Another repeated cluster was located in the 5' flanking sequences, approximately 6 Kb upstream from the first exon. The nucleotide sequence analysis indicated that these repeated sequences are members of the Alu family. The homology between the sequences of the intron 4 and the Alu consensus was 86%. The Alu member studied was oriented in the direction of transcription of the Tg.
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页码：321 / 324
页数：4
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