SELECTIVE SAMPLING FROM THE INFERIOR PETROSAL SINUS - A COMPARISON OF CRF AND TRH STIMULATION

被引：1
|
作者：
SCHILD, H [1 ]
STRACK, T [1 ]
STRUNK, H [1 ]
MILDENBERGER, P [1 ]
SCHREZENMEIR, J [1 ]
KAHALY, G [1 ]
BEYER, J [1 ]
机构：
[1] UNIV MAINZ,INNERE MED ABT,INNERE MED ABT,W-6500 MAINZ 1,GERMANY
来源：
FORTSCHRITTE AUF DEM GEBIETE DER RONTGENSTRAHLEN UND DER NEUEN BILDGEBENDEN VERFAHREN | 1993年 / 158卷 / 01期
关键词：
BLOOD SAMPLING; INFERIOR PETROSAL SINUS; CRF-STIMULATION; TRH-STIMULATION; PITUITARY DISEASE;
D O I：
10.1055/s-2008-1032598
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
In 10 patients with hypophyseal Cushing microadenomas, selective bilateral sampling from the inferior petrosal sinuses was performed and the effect of stimulation by iv TRH and CRF was compared. On the side of the microadenoma, ACTH concentration rose from 650 +/- 242 pg/ml to 2712 +/- 843 pg/ml following injection of CRF and 2025 +/- 242 pg/ml after TRH. Controlateral values were 165 +/- 79 pg/ml, 490 +/- 200 pg/ml and 165 +/- 72 pg/ml respectively. Prolactin concentration on the side of the adenoma was 98 +/- 49 ng/ml before stimulation, 236 +/- 62 ng/ml after CRF and 747 +/- 168 ng/ml after TRH. Contralateral concentration was 22 +/- 10 ng/ml, 64 +/- 19 ng/ml respectively. Sampling localised all adenomas correctly, whereas contrast-enhanced MRT diagnosed only four adenomas.
引用
收藏
页码：43 / 45
页数：3
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