SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF DEMECLOCYCLINE USING SODIUM MOLYBDATE AS ANALYTICAL REAGENT

被引：0
|
作者：
JELIKICSTANKOV, M
STANKOV, D
MALESEV, D
RADOVIC, Z
机构：
[1] CLIN CTR DR DRAGISA MISOVIC, DEPT BIOCHEM, YU-11000 BELGRADE, YUGOSLAVIA
[2] UNIV BELGRADE, FAC PHARM, INST PHYS CHEM, YU-11000 BELGRADE, YUGOSLAVIA
来源：
MIKROCHIMICA ACTA | 1991年 / 1卷 / 1-2期
关键词：
DEMECLOCYCLINE; SODIUM MOLYBDATE; SPECTROPHOTOMETRY; LEDERMYCIN TABLETS;
D O I：
暂无
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
By means of spectroscopic methods it has been found that demeclocycline reacts with molybdate ions forming a complex compound [MoO3HDMTC]2-. The relative stability constant of this compound has been determined by applying spectrophotometric methods. Under optimum conditions for complex formation a very senstivie spectrophotometric method for the estimation of demeclocycline in the concentration range 5.0-35.1-mu-g/ml is proposed. The detection limit of the method is 2.5-mu-g/ml of demeclocycline. The relative standard deviation (n = 10) varies between 0.76% and 1.46%. The method proved to be accurate and sensitive for the analysis of the demeclocycline content in tablets.
引用
收藏
页码：65 / 70
页数：6
相关论文
共 50 条
  • [41] Spectrophotometric determination of phosphate using sodium molybdate and its field application to the simultaneous measurement with ammonium in seawater
    Lin, Kunning
    Huang, Shuyuan
    Wei, Chuanjie
    Jiang, Ronggen
    Xu, Jin
    Zhang, Yuanbiao
    Zhang, Ping
    SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 330
  • [42] Development of a reliable analytical method for the precise extractive spectrophotometric determination of cadmium(II) by using of chromogenic reagent: analysis of real samples
    Nalawade, Avinash M.
    Nalawade, Rekha A.
    Shejwal, Rajendre, V
    Kamble, Ganesh S.
    Ling, Yong-Chein
    Anuse, Mansing A.
    INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY, 2022, 102 (16) : 4158 - 4177
  • [43] SIMULTANEOUS DETERMINATION OF URANIUM AND THORIUM USING 4-(2'-THIAZOLYLAZO)RESACETOPHENONE OXIME AS ANALYTICAL REAGENT - A DERIVATIVE SPECTROPHOTOMETRIC METHOD
    RAMESH, A
    KRISHNAMACHARYULU, J
    RAVINDRANATH, LK
    RAO, SB
    JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY-ARTICLES, 1993, 170 (01): : 181 - 187
  • [44] NICOTINAMIDOXIME AS AN ANALYTICAL REAGENT .1. SPECTROPHOTOMETRIC DETERMINATION OF URANIUM WITH NICOTINAMIDOXIME
    TRIPATHI, KK
    BANERJEA, D
    FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1959, 168 (05): : 326 - 330
  • [45] ERIOCHROME BLACK T - A NEW ANALYTICAL REAGENT FOR SPECTROPHOTOMETRIC DETERMINATION OF SULPHANILAMIDES
    Smolinska, Maria
    Korkuna, Olga
    Vrublevska, Teodozia
    Teslyar, Grigory
    CHEMISTRY & CHEMICAL TECHNOLOGY, 2015, 9 (04): : 401 - 410
  • [46] THIOVIOLURIC ACID AS AN ANALYTICAL REAGENT - SPECTROPHOTOMETRIC AND COMPLEXOMETRIC DETERMINATION OF COPPER(II)
    SINHA, PP
    CHAWLA, RS
    SINDHWANI, SK
    KAMIL, F
    REVUE ROUMAINE DE CHIMIE, 1981, 26 (06) : 917 - 923
  • [47] Flow injection spectrophotometric determination of As(III) and As(V) using molybdate reagent with solid phase extraction in-valve column
    Grudpan, K
    Worakijcharoenchai, N
    Sooksamiti, P
    Jakmunee, J
    Christian, GD
    INDIAN JOURNAL OF CHEMISTRY SECTION A-INORGANIC BIO-INORGANIC PHYSICAL THEORETICAL & ANALYTICAL CHEMISTRY, 2003, 42 (12): : 2939 - 2944
  • [48] 2-THIOPHENHYDRAZIDE AS ANALYTICAL REAGENT - SPECTROPHOTOMETRIC DETERMINATION OF PD(II)
    GIMENEZPLAZA, J
    PAREJAJIMENEZ, JM
    AFINIDAD, 1979, 36 (360) : 151 - 155
  • [49] SPECTROPHOTOMETRIC DETERMINATION OF PALLADIUM .2. BISMUTHIOL II AS AN ANALYTICAL REAGENT
    MAJUMDAR, AK
    CHAKRABARTTY, MM
    ANALYTICA CHIMICA ACTA, 1958, 19 (05) : 482 - 487
  • [50] THYMOLPHTHALIN AS AN ANALYTICAL REAGENT .1. SPECTROPHOTOMETRIC DETERMINATION OF FERRICYANIDE AND FERROCYANIDE
    ELSHAHAT, MF
    ELSAYED, AB
    ABDELBADIE, MM
    AMER, AI
    JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 1986, 33 (01) : 49 - 53
12345