INFLUENCE OF VACCINATION ON LOCAL IMMUNITY CHARACTERISTICS - DETERMINATION OF ANTIMENINGOCOCCAL ANTIBODIES IN SALIVA

被引：0
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作者：
MARTYNOV, YV
MARININ, IY
DEVYATKINA, NP
机构：
来源：
ZHURNAL MIKROBIOLOGII EPIDEMIOLOGII I IMMUNOBIOLOGII | 1991年 / 10期
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中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Local immunity characteristics were studied in 130 young males; of these, 80 had been immunized with group A meningococcal vaccine. In nonstimulated saliva, collected prior to vaccination, then on days 7, 14 and 30 after vaccination, the levels of IgA antibodies to group A meningococcol group-specific polysaccharide (PS-A) were determined in the enzyme immunoassay, and secretory IgA and IgA, IgG, IgM were determined by Mancini's method. The study revealed that after the parenteral administration of group A meningococcal vaccine an increase in the concentrations of SIgA and IgA antibodies to PS-A occured. The manifestation of changes in local immunity characteristics in response to meningococcal vaccine depended on the initial level of IgA antibodies to PS-A.
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页码：55 / 58
页数：4
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