Disaggregation Effects Of Blood Vessels On Platelets In Patients With Abdominal Obesity

In modern society there is a tendency to a continuous increase in the number of patients who have abdominal obesity. It was noted that the high incidence of thrombosis in this contingent of patients is largely due to the presence of vasopathy, the characteristics of which are still poorly investigated. The goal is to find out the state of the disaggregation capacity of blood vessels in relation to platelets in patients with abdominal obesity.We examined 46 patients of the second mature age (mean age 52.7 +/- 2.2 years) with abdominal obesity. The control group was composed of 26 clinically healthy people of the same age. All the examined persons gave written informed consent on participation in the research. There were applied biochemical, hematological and statistical methods of investigation. High thromboses' frequency of various localizations at with abdominal obesity is closely connected with angiopathy development against their background. Weakening of plasma antioxidant protection with activation of lipids' peroxidation processes in it leading to alteration of vascular wall, is noted in conditions of abdominal obesity. The persons with abdominal obesity are detected to have evident weakening of disaggregating vascular impacts of vascular wall on strengthening aggregative ability of platelets. In the result of it given patients get sharply increased risk of thromboses of any localization which can lead to invalidism and lethal outcome.