A PRACTICAL, LARGE-SCALE PROCEDURE FOR THE PREPARATION OF N-PROTECTED ALPHA-AMINO KETONES FROM ALPHA-AMINO-ACIDS

被引：18

作者：

KLIX, RC

CHAMBERLIN, SA

BHATIA, AV

DAVIS, DA

HAYES, TK

ROJAS, FG

KOOPS, RW

机构：

[1] Department of Chemical Development, D-54Z Chemical and Agricultural Products Division, Abbott Laboratories North Chicago

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 11期

关键词：

D O I：

10.1016/0040-4039(95)00144-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient multigram-scale method has been developed for the preparation of chiral N-protected alpha-amino ketones from chiral N-protected amino acids. Several examples using this procedure are reported, including a large scale application.

引用

页码：1791 / 1794

页数：4

共 50 条

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