A simple preparation of N-protected chiral alpha-aminonitriles from N-protected alpha-amino acid amides

被引：37

作者：

Maetz, P ^{[1
]}

Rodriguez, M ^{[1
]}

机构：

[1] NEOSYST,F-67100 STRASBOURG,FRANCE

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 24期

关键词：

D O I：

10.1016/S0040-4039(97)00895-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-protected alpha-amino-acid amides are dehydrated to N-protected alpha-aminonitriles in good yields and with excellent purities by reaction of the corresponding primary amides with cyanuric chloride in DMF. (C) 1997 Elsevier Science Ltd.

引用

页码：4221 / 4222

页数：2

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