CHOLECYSTOKININ MESSENGER-RNA DETECTION IN RAT SPINAL-CORD MOTONEURONS BUT NOT IN DORSAL-ROOT GANGLIA NEURONS

被引:21
|
作者
SCHIFFMANN, SN [1 ]
TEUGELS, E [1 ]
HALLEUX, P [1 ]
MENU, R [1 ]
VANDERHAEGHEN, JJ [1 ]
机构
[1] UNIV LIBRE BRUXELLES,ERASME ACAD HOSP,B-1070 BRUSSELS,BELGIUM
关键词
CHOLECYSTOKININ MESSENGER RNA; SPINAL CORD; DORSAL ROOT GANGLIA; MOTONEURON; CALCITONIN-GENE RELATED PEPTIDE;
D O I
10.1016/0304-3940(91)90173-Q
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Cholecystokinin (CCK) mRNA has been detected by in situ hybridization histochemistry using two different oligonucleotide probes in small to medium-sized neurons of layers II-III and X of Rexed and in large neurons of layer IX in the rat spinal cord at cervical, thoracic and lumbo-sacral levels. No labeled cells were detected in the dorsal root ganglia. This confirms the previously established distribution of CCK-like immunoreactivity in layers II-III and X and indicates, in addition, that motoneurons of layer IX may express true genuine CCK whilst conversely, dorsal root ganglia neurons do not.
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页码:123 / 126
页数:4
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