2 DEVELOPMENTALLY REGULATED MESSENGER-RNAS ENCODING ACTIN-BINDING PROTEINS IN PHYSARUM-POLYCEPHALUM

被引：13
|
作者：
STPIERRE, B [1 ]
COUTURE, C [1 ]
LAROCHE, A [1 ]
PALLOTTA, D [1 ]
机构：
[1] UNIV LAVAL,FAC SCI & GENIE,DEPT BIOL,QUEBEC CITY G1K 7P4,QUEBEC,CANADA
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1173卷 / 01期
基金：
加拿大自然科学与工程研究理事会;
关键词：
ALPHA-ACTININ; ACTIN BUNDLING; ACTIN BINDING; (P-POLYCEPHALUM);
D O I：
10.1016/0167-4781(93)90254-B
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A cDNA library from amoebae of Physarum polycephalum was screened by differential hybridization. Two clones contained inserts for mRNAs present in amoebae and absent in plasmodia. The LAV3-4 cDNA encodes a 402 aa protein (ABP-46) that shows sequence similarity to the actin binding site in the N-terminal region of the alpha-actinin family. The LAV3-5 cDNA is 76% identical to the Dictlyostelium actin bundling protein, which cross-links and stabilizes actin filaments in amoebal filopodia.
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页码：107 / 110
页数：4
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