ATRAUMATIC QUANTITATION OF CEREBRAL PERFUSION IN CATS BY F-19 MAGNETIC-RESONANCE-IMAGING

被引：9
|
作者：
BRANCH, CA
EWING, JR
HELPERN, JA
ORDIDGE, RJ
BUTT, S
WELCH, KMA
机构：
[1] Center for Stroke Research, Department of Neurology, Henry Ford Hospital, Detroit, Michigan
来源：
MAGNETIC RESONANCE IN MEDICINE | 1992年 / 28卷 / 01期
关键词：
D O I：
10.1002/mrm.1910280105
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
We have noninvasively produced low‐resolution, quantitative nuclear magnetic resonance images of cerebral blood flow in 2‐ml voxels in eight cats. Typical signal‐to‐noise of 4 to 1 was obtained in cerebral voxels in 16.5‐s epochs. Mean flow during normocapnia (paCO2 = 39 ± 4 mm Hg) and hypercapnia (paCO2 = 62 ± 4 mm Hg) was 53 ± 20 ml/100 gmin and 140 ± 36 ml/100 g‐min, respectively. Fast flows in normocapnia were 94 ± 13 and 182 ± 39 ml/100 g‐min in hypercapnia. These results suggest that an atraumatic quantitative imaging assessment of cerebral perfusion may be possible in humans using these techniques.© 1992 Academic Press,Inc. Copyright © 1992 Wiley‐Liss, Inc., A Wiley Company
引用
收藏
页码：39 / 53
页数：15
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