EFFECTS OF RANITIDINE AND METOCLOPRAMIDE ON GASTRIC FLUID PH AND VOLUME IN CHILDREN

被引：12
|
作者：
CHRISTENSEN, S
FARROWGILLESPIE, A
LERMAN, DJ
机构：
[1] UNIV TORONTO,HOSP SICK CHILDREN,DEPT ANAESTHESIA,555 UNIV AVE,TORONTO M5G 1X8,ONTARIO,CANADA
[2] UNIV TORONTO,HOSP SICK CHILDREN,RES INST,TORONTO M5G 1X8,ONTARIO,CANADA
来源：
BRITISH JOURNAL OF ANAESTHESIA | 1990年 / 65卷 / 04期
关键词：
Anaesthesia: paediatric; Gastrointestinal tract: gastric fluid volume; gastric pH; Premedication:; metoclopramide; ranitidine;
D O I：
10.1093/bja/65.4.456
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
To determine the effects of ranitidine and metoclopramide on gastric fluid in children, 40 healthy children (aged 2-8 yr) were allocated randomly to groups of 10 to receive one of four oral premedications 4 h before surgery: no premedication, metoclopramide 0.1 mg kg-1 ranitidine 2 mg kg-1 and metoclopramide 0.1 mg kg-1 with ranitidine 2mg kg-1. After tracheal intubation, gastric fluid was aspirated and analysed for pH and total fluid volume. Ranitidine, with or without metoclopramide, increased gastric fluid pH significantly compared with control (P < 0.05). Gastric fluid volume did not change significantly. © 1990 Copyright: 1990 British Journal of Anaesthesia.
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页码：456 / 460
页数：5
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